January 2011. An unmasked account of decisions about investing into cancer stem cell research and the fate of regenerative medicine projects in Japan. Dr Busch summarises results and evaluates technology platforms like novel antibodies and wnt mechanisms. He voices his expectations from current key drug development partnerships, in particular with Oncomed and Micromet. Will these include companion diagnostics? To what extent does Bayer retain respective intellectual property rights? A comment on personalised medicine and cancer stem cells research pursued by Merck KGaA and others. What are prospects for classic oncology drugs?
November 2009. “Stem cells provide novel opportunities that didn't previously exist” says Dr Patrick Vallance, Head of GlaxoSmithKline’s Drug Discovery in an interview with B2Bioworld. He describes his company’s approach. What is the role of cancer stem cells? What about novel drugs like lapatinib or trastuzumab? Which collaborations are desirable? The report includes stem cell issues yet unattended by pharma.
February 2009. While many ethical questions surrounding the use of stem cells have been satisfactorily answered, a number of unresolved methodological and technical issues hamper applications in the pharmacceutical industry. Where are the stumbling blocks of today? What is Merck’s and Merck Serono’s approach, and with what prospects?Top 10 Tags
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- Laemmli system
- LanzaTech
- lapatinib
- Large Scale Biology Corporation
- Latterell Venture Partners
- Laurant Palazzo
- Laurence Argimon-Pistre
- law
- LC/MS
- LCAM SAS
- legionella testing
- Lehmann Brothers Holdings Inc.
- Leslie J Saucedo
- Leukaemia & Lymphoma Society
- leukaemia inhibitor
- Lev M. Yagupolskii
- Lialda
- licencing
- licensing
- life'sDHA
- LiFePO4
- LiFePO4 electrode material
- Life Science Partners
- Life Science Research Group
- LightCycler
- lignin
- ligninolytic enzymes
- lignins
- lignocellulose hydrolysis
- lignocellulosic ethanol
- lignocellulosic feedstock
- Lilly Asian Ventures
- Lilly Ventures
- Lilly Ventures Management Company
- Limas Kupčinskas
- LiMPO4
- Lipid Therapeutics GmbH
- liposomal drug delivery
- liquid handling
- Lisa Smolenska
- lithium cobalt oxide
- lithium iron phosphate
- liver
- liver biology
- livestock breeding
- LKB
- LLC
- Lluis Mata Vallespín
- LM Yagupolskii
- lobbying
- long-chain omega-3 fatty acid
- Long V Ngyuen
- Lonza
- Lonza AG
- LT-02
- Ltd.
- lubricants
- luciferase assay
- Lukoil
- Lumis Biotech
- lung cancer
- lutein
- Lys
- LysoPE
- LysoPE-DOCA
- lysophosphatidylethanolamine
- Lämmli system
- L’Oreal
- M&G Group
- M. P. Gelderman
- macula degeneration
- Mads Krogsgaard
- Majid Mehtali
- Malaria
- malaria consortium
- MALDI-ToF
- malt substitution
- mammalian cell culture
- mammalian cell culture perfused
- Manfred Kirchner
- mannose-6-phosphate
- Manuk
- manure
- Mapei SpA
- MAPK
- Marc Grenley
- Marco Squinzi
- Maria-Jose Bravo
- marine biotoxins
- marker-assisted selection
- marker K19
- marketing scientific instruments
- Markey Molecular Medicine Center
- Mark Fishman
- Mark K Malmros
- Mark Skolnik
- Markus Rarbach
- Martek Biosciences
- Martine Aubry
- Martin Schade
- Martin Zeil
- Mary F Lopez
- Mascoma Brasil Pesquisa e Desenvolvimento de Tecnologias de Biomassa Ltda
- mash
- Mashberg
- mass spectra
- mass spectrometry
- Mathias Boehringer
- Mathis ohf
- Mathiwos Wondu
- Matin Qaim
- Matthias Bron
- Maurice Cross
- Mauruce Beaumont
- Max-Planck-Institut für Züchtungsforschung. plant research China
- Maximus Johniti Ongkili
- Max Karner
- Max Reinshagen
- Max S Topp
- maïs
- MCP-1
- media
- media culture
- media development
- Medica
- medical
- medical; pharma; drug delivery; Biopump; Epodure; EPO; erythropoietin; Medgenics; Amgen; Johnson & J
- medical devices
- medical diagnostics
- medical imaging
- Medica Venture Partners
- MediGene AG
- MedImmune
- MedImmune Ventures
- Medtrials Inc.
- Meiji Seika Kaisha
- Meiji Seika Pharma
- Meintrup
- Melamin
- melanoma test
- Mellon Family Investment Company
- membrane peptides
- menococcal vaccine
- Merck
- Merck & Co.
- Merck KGaA
- Merck Rerono
- Merck Santé SAS
- Merck Serono
- Merck Sharp & Dohme
- Merial
- mesalazine
- mesalazine-refractory ulcerative colitis
- Messe Leipzig
- metabolic disorders
- Metanomics Health
- Metavana Inc.
- methanocalculus pumilus
- methicillin
- methicillin-resistant Staphylococcus aureus
- Methylene Blue MMX
- Metro AG
- Mettler-Toledo
- Mettler-Toledo AG
- Mezavant XL
- Michael Athanas
- Michael Foley
- Michael Hamilton
- Michael Kraus
- Michael P Myers
- Michael Zavrel
- Michel Armand
- Michigan Business School
- microalgae
- microalgas
- microarrays
- microbial fermentation
- Microbiology International
- microfluidics
- Micromet
- Micromet AG
- micronutrient fortification
- microorganisms
- microRNA
- microRNA profiling
- midgut stem cells
- Mike Jones
- Mike Mack
- Millenium Development Goals
- Millipore
- mir-302 expression
- MIR604
- MIR604 licence
- miRBase
- mircoarrays
- miRNA
- miRNA arrays
- MixAlco
- model organism plant research
- Mohamedali Azim
- Mohr Davidow Ventures LP
- molecular design
- molecular farming
- Moleküler Biyoloji ve Genetik
- Monsanto
- Morgenthaler Ventures
- MorphoSys
- Mossi & Ghisolfi S.P.A.
- MRC Centre for Regenerative Medicine
- MRSA
- MScout
- MSD
- MS immunoassays
- MS proprietary formats
- MT-103
- multichannel verification
- multimatrix technology
- Multiple Reaction Monitoring
- Munich Biotech
- mutaflor
- MVS
- MWECS
- myocardial infarction
- Myriad Genetics Inc
- Myriad RBM Inc
- Nabucco
- Nadine Igl-Schmid
- Naftagas
- Nagoya Protocol
- NAG Research Laboratories
- nanobiotechnology
- nanocylinder
- nanoparticles
- nanotechnology
- Nateco2
- National Academy of Sciences of Ukraine
- National Institute of Standards and Technology
- National Instruments
- natural product synthesis
- neglected diseases
- Nektar Therapeutics
- Neogen
- Neogen Europe Ltd.
- NEPIC
- Nestec SA
- Nestlé
- neuro analytics
- neurobiology
- neutropenia
- New Enterprise Associates
- New York University
- next-generation sequencing; sequencing
- NIBR
- Niels Teich
- Nikon
- nilotinib
- NimbleGen
- Ning Sun
- Nobilon
- non Hodgkin's lymphoma
- Norbert Riedel
- Norbert Röttgen
- Norit; SüdMo
- noroviruses
- North Carolina
- North East of England Process Industry Cluster
- Novartis
- Novartis Institutes for BioMedical Research
- Novartis Option Fund
- Novartis Vaccines Institute for Global Health
- Novartis Venture Fund
- Novavax
- Novocart
- Novocell
- Novo Nordisk
- Novozymes
- nuclear energy
- nucleic acids
- nutraceuticals
- nutrition
- nutrition; cosmetics
- nutrition industry
- nutrition supplements
- Nycomed
- O2 sensors
- occupational health
- octreotide
- OECD
- oil extraction
- okadaic acid
- okadaic toxin
- Okatest
- Olafur Hedinn Fridjonsson
- oleoresins
- Oliver Fetzer
- Olympus
- Olympus Europe
- oléagineux
- omacetaxine mepesuccinate
- omalizuman
- OMAPRO
- OMC
- omega-3
- omega-6
- OmegaTech
- OMP-21M18
- OMPI
- OMS
- oncogenes
- oncology
- oncology drugs
- Oncomed
- OncoMed Pharmaceuticals
- oncoproteins
- ONDEA
- One Equity Partners LLC
- One West Bank
- Opgen Inc
- ophthalmology
- Optimum
- Orexin type 1
- Organisation des Nations Unies pour l’alimentation et l’agriculture
- Organisation Mondiale de la Proprieté Intellectuelle
- Organisation Mondiale de la Santé
- Organisation Mondiale de Santé
- Organisation Mondiale du Commerce
- orphan drug
- orphan drugs
- Oréal
- OSAGE University Partners
- Osiris
- osteochondral transplantation
- osteodystrophy
- osteogenesis
- osteogenesis imperfecta
- OTC
- Ox1
- oxacillin
- oxazine
- oxazine dye
- Oxford-Emergent-Tuberculosis Consortium
- oxygen measurement
- p53 inhibitor
- PAC-LINK BioVentures
- Pacific Andes
- pain management
- pain therapeutics
- Paion AG
- Pallone intragastrico
- palm oil pathogen prevention
- pancolitis
- Paola Testori-Coggi
- paper industry
- parathyroid hormone
- Parkinson’s
- partnering
- parvoviral gene-transfer
- PAT
- patent cost Japan
- patent econometrics
- patents
- patent system
- patent – biodiversity
- patient organizations
- Patrick Patterson
- Patrick Vallance
- Paul Brown
- Paul E. Schickler
- Paul J Hastings
- PCR plate
- peau reconstruites
- Pecten maximus
- Pedro Razquin Casquero
- penicillin
- Pentasa
- pentose
- people
- peripheral blood
- personalised medicine
- pesticides
- Peter Coffey
- Peter Durkee Meldrum
- Peter Harris
- Peter Heinrich
- Peter Stadler
- Peter Stern
- PETKİM PETRO KİMYA
- petrochemicals
- petroindustry investments
- Pfizer
- Pfizer Genetics
- Pfizer Regenerative Medicine
- Pfizer Strategic Investment Group
- Pfizer Wyeth acquisition
- pharma
- Pharmaceutical Forum
- Pharma China
- Pharmacia Austria
- Pharmacia Biotech
- Pharma India
- pharma manufacturing; pharma; cell cloning; cell culture; screening;
- Philip Haworth
- phosphatase inhibition assay
- Phostech Lithium Inc
- photosynthesis
- photosynthetic microorganisms fatty acids
- phrama
- PHT
- Phycosource Sarl
- phyllosilicate
- Phytophthora infestans
- pi-helices alpha-helices
- PI3K
- Pichia stipitis
- PicTar
- Pierre Amouyel
- Pioneer Hi-Bred
- Piper Jaffray Ventures
- pipette
- plant-made pharmaceuticals
- plant biotechnology
- plant genetic research
- plant research
- plant research India
- Plant Research International
- Plantrose
- plant variety rights
- plasma glucose level regulation
- Plasmid Factory GmbH & Co. KG
- plasmid technology
- plasminogen activator
- plastics
- Plenus S.A. de C.V.
- plug-in hybrid cars
- pluripotent stem cell
- pMel-17
- pMIR-REPORT
- POCT
- Polaris Venture Partners
- Pol Bamelis
- policy
- political correctness
- polyacrylamide gels
- poly adenylation signal
- polycarb
- polycarboxylate superplasticizers
- polyp detection
- Polyphenol
- polyps
- populism GMO
- Possehl Beteiligungsverwaltung GmbH
- Possehl Stiftung
- potagères
- potato
- potato production
- PrairieGold VenCap Fund
- PrairieGold Venture Partners
- predictive medicine
- PreSens Precision Sensing GmbH
- Presens Precision Sensing GmbH; Vaisala Oyi
- private equity; Protagonist Therapeutics Inc.
- process analytical technologies
- process development
- Procter & Gambler
- proctosigmoiditis
- PROESA
- progenitor cells
- Prokarìa ehf
- PRONOVALG Sarl
- prostate cancer
- protein-encoding genes
- protein capture; disposables
- protein electrophoresis
- protein fixation
- protein metabolised
- protein overloading
- proteins-guanine nucleotide exchange
- proteins functional
- proteomics
- Provence Technologies SAS
- Provepharm
- Provepharm SAS
- Pseudomonas entomophila
- pulp
- pulp & paper
- pâtes alimentaires
- Qiagen
- QIC
- quadri-valent vaccines
- Quaker BioVentures Inc
- quantum efficiency
- Queensland Bio Capital Fund
- R&D funding TR
- R&D policy
- R. B. Holtz
- R. O. Brady
- Rachel Blumhagen
- Rachel l Toth
- Radium-223 Chloride
- Radu Mihail Voiosu
- Raf
- Raf1
- RAGT Génétique
- RAGT Semences SAS
- Rapamycine
- rapid testing
- rare diseases
- Ras
- Ras homologues
- Raymond Tucci
- Raymund Breu
- rDSPA alpha 1
- REACH
- Reach Global Services
- REACH regulation
- Rebif
- receptor antagonist
- Receptos Inc.
- reconstruction de la peau
- recruitment
- regenerative medicine
- regenerative medicine pharma
- regenerative medicne
- Regeneron
- regulations
- regulatory
- regulatory affairs
- Remigijus Garalevičius
- Remimazolam
- removal tagged ligands
- renal failure
- Reneuron
- renewables
- Renmatix Inc
- Renovel Discoveries
- Replagal
- research
- resins
- retarded release phosphatidylcholine
- Reteplase
- Reteplase contract manufacturing
- Rett Syndrome
- Rheb
- Rheb effector compounds
- Rheb mRNA
- RhuDex
- RichMac
- Riemser Arzneimittel
- RISC
- riz
- RK Ventures
- RNA-induced silencing complex
- Robert Erwin
- Robert l Erwin
- Robert Mugabe
- robotics
- Roche
- Roche Diagnostics
- Roche Finance Ltd.
- Roche Kapitalmarkt AG
- Roche Molecular Systems
- RocheNimbleGen
- Roche Ventures
- Rohm & Haas
- rolling circle amplification
- Romualdas Jurgutis
- root worm
- Rouergue Auvergne Gevaudan Tarnais SA
- Royal Greenland Seafood
- Royal Society of Chemistry
- rPHT1-34
- Rudi Beyaert
- Rules-based Medicine
- Ruth McKernan
- S. J. Garger
- Sachsen-Anhalt biomanufacturing
- Sadao Nagaoka
- Safeguard Scientifics Inc.
- safflower seed oil
- safinamide
- Sahram Emady-Azar
- Salix Pharmaceuticals Inc
- salmon husbandry
- Salofalk
- Sanderling Ventures
- Sandostatin
- Sandoz
- Sandra E. Peterson
- Sandra Hoffmann
- Sandro Aruffo
- San Francisco; Bayer U.S. Innovation Center
- sanitation monitoring
- Sanofi
- Sanofi-Aventis
- satiation
- Sayah
- SBA
- SC4M
- Scanbio
- Scanlab
- SC Biomed Plus srl
- Schering-Plough
- Schering; Bayer Schering
- Schweizerische Gesellschaft für Chemische Industrie
- science
- Science Magazine
- science prize
- Scientific Devices Heidelberg GmbH
- scientific instrumentation
- Scil Proteins revenues
- Scil Technology
- Scottish bivalve biotoxin monitoring
- screening
- SDS-PAGE
- Sean Chapman
- Sebastian Freitag
- Sebastian Tegethoff
- Securities and Exchange Commission; Biomet 3i de Brasil Ltda.
- seeds
- Selected Reaction Monitoring
- semences
- sensors
- separation techniques
- Sequel Venture Partners
- sequencing
- sequencing – electrophoresis
- Sequenom
- Seyonic SA
- SGCI
- SGS
- SGS SA
- Sharon Hashmuele
- Shell Deutschland
- shellffish toxins
- shellfish
- Shimadzu
- Shire
- SIAL
- SIEF
- Siemens
- SightLine Partners LLC
- Sigma-Aldrich Biotechnology L.P.
- Sigma Aldrich
- signal capture
- signalling pathway
- signal transduction
- Silence Therapeutics plc
- silicane-based nanoparticles
- Silliker France
- sinecatechin
- SIOGEN Biotech Pvt. Ltd.
- Siosomes
- siRNA
- skin
- small cell lung cancer
- smart agriculture
- smart farming
- SME and REACH
- soap
- SOCAR
- Society of Chemical Industry
- Società Italiana di Endoscopia Digestiva
- Société RAGT 2N SAS Bayer Crop Science AG
- soja
- solvent washng
- somatic cell reprogramming
- sonepcizumab
- sorbitol
- soya Argentina
- soya protein
- spectral sensitivity
- Spencer Trask Emerging Technologies Group LLC
- spices
- spirella
- spray dried algal meal
- Sprycel
- Sri Kilambi
- Sriya Innovations
- SRM
- SR One
- St. James’s Brewery
- staining techniques
- staining tehniques
- Stammzellpatente
- standardization of stem cell assays
- standards mass spectra
- starch industry
- Starfish Ventures
- Start-up Australia Ventures Pty Ltd.
- state aids Turkey
- Stefan Borgas
- Stefan Herr
- Stefanie Howaldt
- Stefan Marcinowski
- Stefan Oschmann
- Stefan Schreiber
- stem cell assay
- stem cell assays
- stem cell bioprocessing
- stem cell differentiation
- stem cell ethics
- stem cell identification
- stem cell media
- stem cell media; assay development; cardiomyocytes; media development; regenerative medicine; embryo
- stem cell medium
- stem cell patents
- stem cells
- Stem Cells 4 Safer Medicines
- Stem Cell Sciences
- Stem Cells for Safer Medicines
- stem cells industrial use
- stem cells standardization
- stem cell technologies
- StemCell Technologies Inc
- Stemcell Technologies Inc.
- Stemcell Technologies Sàrl
- stem cell therapy
- STEMcircle
- stent
- Stephan Kühne
- sterile tips
- Steven Stein
- Steven Suchyta
- Steven V Ley
- stimuvax
- Substance Information Exchange Forum
- Sue Greenwood
- sugar feedstock
- sugars
- sunliquid
- supercritical CO2
- surgery
- Susan Desmond-Hellmann
- Swiss Biotech Association
- Sylviane Oguey-Araymon
- SyncoBioPartners
- Syngas
- Syngenta
- Syngenta Seeds
- synthesis natural products
- Synthetic Genomics Inc
- Søren Halskov
- Süd-Chemie
- Süd-Chemie AG
- Süleyman Gülsüner
- T-RP2
- T315I Bcr-Abl
- Taconic
- Taha Rezai
- Tajikistan
- Takahisha Matsuda
- Takeda
- target identification
- TargetScan
- Tasigna
- Tayfuin Özçelik
- Tecan AG
- TECAN Group AG
- Tecan U.S. Group Inc
- Tecan US
- technique régénératrice
- Technische Universität München
- technology transfer reversed
- tectosilicate
- TeLA GmbH
- Telethon
- teQstart Pty. Ltd.
- Tereos
- Teresa Garzón
- teriparatide
- Terry W. Hermiston
- Tesco
- Tesla
- TETEC AG
- textile
- textile industry Turkey
- textiles
- TGN1412
- Thayalan
- The Institution of Chemical Engineers
- The Invus Group
- Thermo Fisher
- The Vertical Group
- thiazine dye
- Third Rock Ventures
- Thomas Klaue
- Thraustochytrids
- thrombolysis
- thrombolytic therapy
- ThyssenKrupp AG
- Tikur Anbessa
- Timur Erk
- tissue engineering
- tissue profiling
- tissue regeneration
- tissue repair
- TKSD
- tolbutamide
- toluidine blue
- TOR
- TOR signalling
- toxicity
- toxicity screening
- toxicity testing
- toxicity testing: veterinary
- Toxiline-DSP.Co
- toxins
- trade fair management
- trade fairs
- trade fairs China
- trade show
- traditional cultural expressions
- traditional knowledge
- Trametes hirsuta yj9
- transgenic breeding
- transgenic crops
- transgenic plants
- transgenic plants; Michiel van Lookeren Campagne
- transgenèse
- Transkaryotic Therapies Inc
- trastuzumab
- triazolotriazine; triazolopyrazines
- trilateral patent system
- Trinity Biosystems
- TRIPs
- Trust Property Research
- TSC1/2
- Tuberous sclerosis
- Tucci
- tucotuzumab
- tumor suppressor gene
- tuna industry
- Turkish Chemicals Industry Association
- Turkish Kidney Foundation
- tyrosine kinase inhibitor
- TÜBITAK
- Tüpraş
- Türkiye Kimya Sanayicileri Derneğine
- UASRheb
- UBS AG
- Udo de Wall
- UICC
- UK and euro zone
- UK banking sector
- UK chemical industry
- UK dependence on dollar
- UK nutrition industry
- UK pharmaceutical industry
- Ukraine
- Ulrich Kettling
- umbilical cord blood
- UN
- Uner Tan Syndrome
- Unilever
- Union for International Cancer Control
- United Nations
- University of Bradford
- University of California
- University of Edinburgh – stem cells
- University of Stanford
- University of Washington
- Universität Frankfurt
- Universität Tübingen
- Université de Montreal
- unregistered trading
- UPOV
- upstart ventures
- Urs Lüthi
- ursodeoxycholate
- US biotechnology sector
- US government
- US Patent and Trademark Office
- US PTO
- US Venture Partners
- UV lithography
- Uzbekistan
- vaccines
- Vaisala Oyi
- Valero Energy Corporation
- Valero Renewable Fuels Company
- valuing patents
- Varian
- VBio
- VCI
- Vendela Parrow
- Venrock Inc.
- venture capital
- venture investment
- venture valuation
- Verband der Chemischen Industrie
- Veregen
- VeroMara
- Versant Ventures
- veterinary vaccines
- Viamet Pharmaceuticals Inc.
- ViiV Healthcare
- Vincent Duvillier
- viral homologous recombination
- Virbac
- Vivalis
- Volkswagen
- Wacker Química do Brasil Ltda.
- Walter Stremmel
- Wasatch Advisors Inc.
- Waters
- water testing
- West Nile virus
- Wexford Capital LLC
- WFP
- WFR Capital
- wheat seeds market
- wheat traits
- whey protein
- Whitehead Institute for Biomedical Research
- WHO
- whole-plant system
- Wilex AG
- William A Frezza
- wingless Drosophila
- winter wheat
- WIPO
- wnt
- World Economic Forum
- World Health Organization
- World Intellectual Property Organization
- World Social Forum
- World Trade Organization
- W Shermal Perera
- WTO
- Wyeth
- Wyeth takeover
- Wyser-Pratte
- X! Tandem
- Xcelligence
- xCELLigence RTCA HT
- Xiao-feng Liu
- Xyl7A
- xylanase thermostable
- xylanolitic enzymes
- xyloglucan
- YA Abassi
- Yasuda Enterprise Development
- YeEthiopia Cancer Society
- Young Ambassador
- Yue-xiang Yuan
- Z.E.U-INMUTEC S.L.
- ZAFES
- Zdravko Dragovic
- ZeaChem
- ZeaChem Applied Technology
- ZeaChem Boardman Biorefinery Operations
- Zeachem process
- zeaxanthin
- Zentrum für Molekulare Biologie
- Zentrum für Sonnenenergie- und Wasserstoff-Forschung
- zeolite
- Zero Hunger program
- ZEU
- Zhai Huqu
- Zhi-ying Yan
- Zila Inc
- Zimbabwe
- Zoser B Salama
- Zsuzsanna Jakab Ferencné
- Zymark Corporation
- Üner Tan
- ácido okadaico
- İstanbul Kimyevi Maddeler ve Mamülleri İhracatçıları Birliği
- α-Gal A
- β3-peptide inhibitors
- ІНСТИТУТ ОРГАНІЧНОЇ ХІМІЇ
- АД Синиця
- ВІ Кальченко
- ВІ Станінець
- ВЮ Пашинник
- ЛМ Ягупольський
- МЙ Поволоцький
- МО Лозинський
- НАЦІОНАЛЬНОЇ АКАДЕМІЇ НАУК УКРАЇНИ
- ОІ Толмачев
- ОМ Пінчук
- ОО Іщенко
- ЮГ Шермолович
- ЮЛ Ягупольський
- ЮО Сергучов